Dealing a blow to the Chinese firm, Google has blocked Huawei, phone maker from some updates to the Android operating system.
Consequently, new designs of Huawei smartphones are going to lose access to some Google apps.
The move comes after the Donald Trump administration added Huawei to a long list of companies that American firms cannot trade with unless they have a licence.
Google said it was “complying with the order and reviewing the implications”, in a statement.
Existing Huawei smartphone users will now be able to update apps and push through security fixes, as well as update Google Play services.
However, when Google launches the subsequent version of Android later on in the year, it may not be available on Huawei devices.
Future Huawei devices may no longer have great apps such as YouTube and Maps.
However, Huawei can still use the version of the Android operating system available through an open source licence.
From the CCS Insight consultancy, Ben Wood said the move by Google would have “big implications for Huawei’s consumer business”.
And last Wednesday the Donald Trump administration added Huawei to its “entity list” which bans the company from acquiring technology from US firms without government approval.
Huawei chief executive Ren Zhengfei told Japanese media on Saturday, in his first comments since being placed on the list: “We have already been preparing for this.”
He said the firm, which buys about $67bn (£52.6bn) worth of components each year according to the Nikkei business newspaper, would push ahead with developing its own parts.
Huawei faces growing backlash from Western countries, led by the US, over possible risks that could pop by using its products in next-generation 5G mobile networks.